Table 3 Disease pattern in PbAus-infected C57BL/6Aus mice treated with 2 × 5 mg/kg/d rtemisone.
Group | Compound | Treatment* (days post-inoculation) | Disease pattern | |||
|---|---|---|---|---|---|---|
| Â | Â | Â | Latency, days | Cerebral malaria | Anemic malaria | Cured** |
1 | - | - | 0 | 5/6 | 1/6 | - |
2 | DMSO (25 μl) | 3-8 | 0 | 3/6 | 3/6 | - |
3 | Artemisone | 3-8 | 10 (n = 1)†| 0/6†| 1/6 | 5/6†|
4 | Artemisone | 4-8 | 11 (n = 1) †| 0/6†| 1/6 | 5/6†|
5 | Artemisone | 5-8 | 10 (n = 4) †| 0/5†| 3/5‡ | 2/5†,‡ |