Figure 5

Lack of correlation between blood levels of soluble ICAM-1 (y-axis) and monocyte cell-surface ICAM-1 (x-axis) in children with malaria. Filled circles represent patients with uncomplicated malaria (n = 50), crosses represent patients with cerebral malaria (n = 33), and triangles represent patients with severe malarial anaemia (n = 52). Ovals represent interquartile ranges of data for each group in each dimension. Overall there is little correlation between soluble and cell-surface values. However, values cluster according to patient groups. Patients with either cerebral malaria or severe malaria anaemia have higher soluble ICAM-1 levels compared with uncomplicated malaria. Monocyte ICAM-1 levels are higher in cerebral malaria patients compared with severe malaria anaemia patients.