Table 1 Diagnostic performance of fluorescent microscopy (CyScope®) and the lateral-flow reagent strip (Paracheck-Pf®) using light microscopy (double reads) as gold-standard.
FLUORESCENT MICROSCOPY V. LIGHT MICROSCOPY | PARACHECK-PF V. LIGHT MICROSCOPY | ||
|---|---|---|---|
468 ADULTS AND 836 CHILDREN | 546 ADULTS AND 951 CHILDREN | ||
Adults | Sensitivity (%) | 86.7 (79.3 - 92.2) | 91.9 (85.9 - 95.9) |
Specificity (%) | 38.8 (33.6 - 44.1) | 98.1 (96.2 - 99.2) | |
PPV (%) | 32.8 (27.7 - 38.3) | 93.9 (88.4 - 97.3) | |
NPV (%) | 89.4 (83.4 - 93.8) | 97.3 (95.3 - 98.7) | |
Children | Sensitivity (%) | 92.1 (89.6 - 94.1) | 98.4 (97.2 - 99.2) |
Specificity (%) | 28.6 (22.8 - 34.9) | 96.2 (93.1 - 98.2) | |
PPV (%) | 77.1 (73.9 - 80.2) | 98.5 (97.3 - 99.3) | |
NPV (%) | 57.9 (48.3 - 67.1) | 95.8 (92.7 - 97.9) |