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Figure 3 | Malaria Journal

Figure 3

From: Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya

Figure 3

Prevalence of pfdhps haplotypes with respect to codons 436, 437, 540, 581, and 613. (A) Prevalence of pfdhps haplotypes that are wild-type at all five codons (WT), single or double mutant with respect to A437G and K540E (SM or DM), single mutant with three additional mutations at codons 436, 581, and 613 (SM + 3), or double mutant with one, two, or three additional mutations (DM + 1, 2, or 3). (B) Distribution of mutations at codons 436, 581 and 613 in the baseline (study period 1) and follow-up (study period 2) studies among isolates that are A437G/K540E double mutant with one additional mutation. (C) Distribution of mutations at codons 436, 581 and 613 in the follow-up study among isolates that are A437G/K540E double mutant with two additional mutations.

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Malaria Journal

ISSN: 1475-2875

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