Evaluation of in vivo Antiplasmodial Activities of extracts of Morinda morindiodes (Bak.) in the treatment of malaria in Ogun State

Table 2 Chemosuppression and survival time of P. berghei infected mice treated orally with Morinda morindiodes extracts at a dose of 100mg/kg body weight twice a day for 5 days

Plant part	Extract	%chemosuppression of parasitaemia at day 5 (C.P.±S.D)	%chemosuppression of parasitaemia at day 11 (C.P.±S.D)	Mean Survival time (days)
Leaf	MeOH	20 ±16.9a	83.7±8.5^c	21.5
Water	5.0 ± 5.6^ab	76.1 ± 1.4^bc	17.5
F.M. starch	27.5 ± 2 8^abc	79.4 ± 24.1^bc	17.5
Stem	MeOH	1.3 ± 11.3^a	73.2 ± 25.4^b	16.5
Water	2.5 ±28.2^a	71.2±2.8^b	16.5
F.M. starch	10.0±5.6^ab	76.5 ± 9.9^bc	17.5
Root	MeOH	35 ± 5.6^bc	80.4±28.2^bc	19.5
Water	70.0 ± 2.8^de	85.9±8.4^bc	21.5
F.M. starch	56.2 ± 7.1^cd	85.6±8.4^c	17.5
Chloroquine		100 ± 0.0^e		28.5
Artesunate		100 ± 0.0^e		28.5
Control		0.0		14.5

MeOH, methanol extract; F.M. starch, "aqueous fermented maize starch ('omidun') extract".

ISSN: 1475-2875