Figure 3From: 2-tert-butyl-primaquine exhibit potent blood schizontocidal antimalarial activity via inhibition of heme crystallization(abstract P69). Effects of heme-induced hemolysis by drugs. (A) Suspensions of erythrocytes were incubated in the presence of heme (final concentrations ranged from 0 to 20 μM) without (open circles) or with 10 μM CQ (closed circles), 10 μM PQ (open triangles), or 10μM BPQ (closed triangles). (B) Suspensions of erythrocytes were incubated in the presence of 10 μM of heme with various concentrations of the drug CQ (closed circles), PQ (open triangles), or BPQ (closed triangles). Error bars indicate standard deviations.Back to article page