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Table 3 The pattern of combined P. falciparum dhfr–dhps haplotypes

From: High-level Plasmodium falciparum sulfadoxine-pyrimethamine resistance with the concomitant occurrence of septuple haplotype in Tanzania

Pfdhps haplotypes

Pfdhfr haplotypes

Total

Wild-type

Double

Triple

CNCSI

CICNI

CIRSI

CNRNI

CIRNI

Wildtype

SAKAA

0

4

0

2

20

26

Single

AAKAA

1

3

0

4

16

24

SAEAA

0

0

0

0

4

4

SAKAS

0

0

0

0

1

1

Double

SGEAA

0

5

0

0

31

36

AAKAS

0

0

0

0

2

2

Triple

SGEGA

0

1

0

0

32

33

AGEAA

2

14

1

10

69

96

Quadruple

AGEGA

0

1

0

0

11

12

Total

 

3

28

1

16

186

234

  1. The overall numbers (absolute) parasite haplotypes on the Pfdhfr–Pfdhps genes in the samples successfully analysed (n = 234). Of all the combined haplotypes, the quintuple CIRNI-SGEAA, sextuple CIRNI-AGEAA, CIRNI-SGEGA were more frequently detected
  2. Bold underline indicates the amino acid changes, while SAKAA and CNCSI represent the wildtype haplotype for Pfdhps and Pfdhfr, respectively
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Malaria Journal

ISSN: 1475-2875

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