Fig. 2

Plasma levels of haemin and cell-free haemoglobin are associated with disease outcome in severe malaria. Children who died of SM, either SMA or CM, had higher plasma levels of haemin and cell-free haemoglobin at presentation compared to children who survived SM. Levels of haemopexin and haptoglobin were lower than those observed in children with UM but were not significantly different between those who survived SM and those who did not. The dotted lines indicate the median levels observed in children with UM. Mann–Whitney test, *p < 0.05