Table 3 Estimates of DNA sequence polymorphism and tests of neutrality for pvs48/45
From: Global genetic diversity of the Plasmodium vivax transmission-blocking vaccine candidate Pvs48/45
Country | Total isolates | SV sites | PI sites | # Mutations | K | H | Hd ± SD | π ± SD | dN | dS | Reference |
|---|---|---|---|---|---|---|---|---|---|---|---|
Mexico | 15 | 0 | 2 | 2 | 0.441 | 2 | 0.221 ± 0.121 | 0.00033 ± 0.00033 | 0.00042 | 0.00000 | This study |
Honduras | 12 | 3 | 2 | 5 | 1.128 | 4 | 0.445 ± 0.170 | 0.00123 ± 0.00094 | 0.00136 | 0.00077 | This study |
Colombia | 60 | 3 | 4 | 7 | 1.929 | 9 | 0.841 ± 0.024 | 0.00188 ± 0.00073 | 0.00185 | 0.002 | This study |
Peru | 24 | 1 | 2 | 3 | 0.372 | 3 | 0.218 ± 0.103 | 0.00034 ± 0.00046 | 0.00045 | 0.00000 | This study |
Brazil | 13 | 2 | 1 | 3 | 0.59 | 4 | 0.526 ± 0.153 | 0.00058 ± 0.00062 | 0.00019 | 0.00194 | This study |
Latin America | 124 | 3 | 5 | 8 | 1.228 | 11 | 0.610 ± 0.047 | 0.00168 ± 0.00087 | 0.00176 | 0.00151 | This study |
Myanmar | 8 | 2 | 5 | 7 | 2.722 | 5 | 0.889 ± 0.071 | 0.00216 ± 0.00110 | 0.00282 | 0.0000 | This study |
Thailand | 18 | 5 | 4 | 9 | 1.392 | 5 | 0.484 ± 0.138 | 0.00116 ± 0.00101 | 0.00103 | 0.00085 | This study |
South Korea | 86 | 0 | 2 | 2 | 0.716 | 3 | 0.611 ± 0.026 | 0.00053 ± 0.00004 | 0.00069 | 0.00000 | [17] |
North Korea | 46 | 2 | 7 | 9 | 1.987 | 5 | 0.0018 ± 0.042 | 0.00147 ± 0.00069 | 0.00029 | 0.00186 | [18] |
Worldwide | 282 | 7 | 5 | 12 | 1.047 | 15 | 0.686 ± 0.00149 | 0.00173 ± 0.00149 | 0.00188 | 0.00149 | This study |