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Table 2 Descriptions of different immunological responses often discussed in malaria epidemiology (after Schofield and Mueller)

From: Large contractors in Africa: conundrums with malaria chemoprophylaxis

Clinical immunity

Acquired immunity that protects against clinical illness despite presence of malaria parasites in blood

Clinical tolerance

Lowered responsiveness to malaria parasite toxins

Anti-toxic immunity

Acquired immunity that neutralizes parasite toxins

Anti-parasite immunity

Acquired immunity that kills or inhibits growth or replication of malaria parasites

  1. Use of such terminology in the scientific literature often overlaps, is sometimes used interchangeably, and can vary subtly in its various applications
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Malaria Journal

ISSN: 1475-2875

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