Glucose-6-phosphate dehydrogenase deficiency among Yemeni children residing in malaria-endemic areas of Hodeidah governorate and evaluation of a rapid diagnostic test for its detection

Table 4 Predictors of G6PD deficiency among children in Hodeidah according to the cut-off activities used to determine the enzyme deficiency

Variable^b	G6PD cut-off activity of ≤30 % (≤1.5 U/gHb)^a
Variable^b	N	n (%)	OR (95 % CI)	p value
Gender
Male	219	28 (12.8)	2.5 (1.18–5.31)	0.014
Female	181	10 (5.5)	Reference
District of residence
Ad Durayhimi	141	21 (14.9)	2.5 (1.27–4.89)	0.007
Al Marawi’ah	259	17 (6.6)	Reference
Consanguinity between parents
Yes	157	22 (14.0)	2.3 (1.17–4.56)	0.013
No	243	16 (6.6)	Reference

OR odds ratio, CI confidence interval, U/gHb units per gram haemoglobin
^aCalculated from the median value of 5.0 that is equivalent to 100 % activity
^bAll variables were confirmed as independent risk factors using stepwise forward logistic regression

ISSN: 1475-2875