Genetic diversity and natural selection of Plasmodium vivax multi-drug resistant gene (pvmdr1) in Mesoamerica

Malaria Journal

Table 3 F_ST values of P. vivax, using the mdr1 gene fragment, within Mesoamerica and between different geographic sites

	SMX	NIC-NE	NIC-NW	HON	BRZ	MD	IND	SLK	ECU	IR-PK	AFR
NIC-NE	0.716
NIC-NW	0.803	0.097
HON	0.113	0.632	0.708
BRZ	0.015	0.615	0.698	0.064
MD	0.943	0.609	0.609	0.825	0.818
IND	0.549	0.580	0.671	0.381	0.392	0.774
SLK	0.694	0.518	0.582	0.511	0.543	0.613	0.180
ECU	0.149	0.701	0.780	0.194	0.136	0.897	0.498	0.655
IR-PK	0.790	0.621	0.721	0.631	0.613	0.864	0.145	0.169	0.735
AFR	0.668	0.478	0.524	0.510	0.544	0.477	0.203	−0.011	0.639	0.144
NEP	0.685	0.578	0.670	0.514	0.518	0.777	0.055	0.090	0.642	0.021	0.100

The fragment comprising 477 bp was analysed (nt 2773–3249)
SMX southern Mexico, NIC-NE Northeast Nicaragua, NIC-NW Northwest Nicaragua, HON Honduras, BRZ Brazil, ECU Ecuador, IR_PK Iran and Pakistan, IND India, SLK Sri Lanka, NEP Nepal, AFR Africa, which includes Sudan (n = 4), Cameroon (n = 8) and São Tomé (n = 3), MD Madagascar

ISSN: 1475-2875