Fig. 2

Dose-response curves describing relationship between concentration of methylene blue (in logarithmic scale) and percentage inhibition of a early stage gametocytes of RKL-9 b late stage gametocytes of RKL-9 c early stage gametocytes of JDP-8 d late stage gametocytes of JDP-8 (Error bars denote SD of the mean of three independent experiments). Gametocytaemia at start of drug screening experiments [In (Mean ± SD)%, RKL-9: Total G: (2.65 ± 0.36)%, Early G: (0.79 ± 0.14)%, Late G: (1.86 ± 0.23)% and JDP-8: Total G: (2.57 ± 0.35)%, Early G: (0.61 ± 0.18)%, Late G: (1.95 ± 0.21)%] where Early G and Late G represents the percentage of early (Stage II and III) and late stage (stage IV and V) gametocytes respectively and Total G represents total gametocytes inclusive of early and late stages. % Gametocytaemia calculations are per 5000 RBCs