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Table 1 Correlation between parasitaemia and sample applicability for direct WGS

From: Direct whole-genome sequencing of Plasmodium falciparum specimens from dried erythrocyte spots

Parasitaemia

Applicable count

Applicable %

Inapplicable count

Inapplicable %

< 10,000

28

58

20

42

10,000

48

72

19

28

20,000

5

100

0

0

30,000

20

74

7

26

40,000

24

77

7

23

> 50,000

19

90

2

10

  1. OR = 1.29 (95% CI 1.07–1.58) p = 0.009
  2. Correlation between parasitaemia and sample applicability for direct WGS N = 199, parasitaemias are given as parasites/µl, calculated according to a leukocyte count of 8000 per µl whole blood. Parasites and leukocytes were counted by microscopy, counting until 500 parasites or 200 leukocytes. Samples were grouped in five groups according to parasitaemia, corresponding to intervals of 10,000 parasites/µl. The minimum parasitaemia recorded in group 1 was 800 parasites/µl, and the maximum parasitaemia recorded in group 5 was 81,633 parasites/µl. Applicable/inapplicable count corresponds to the number of samples. Logistic regression was performed to investigate the relationship between parasitaemia of the infection and applicability of the sample for WGS. OR (odds ratio), CI (confidence interval) and pI-value (p) are given