Structural patterns of selection and diversity for Plasmodium vivax antigens DBP and AMA1

Malaria Journal

Table 1 Population genetics parameters for PvAMA1 sequences from various geographic locations

Country	n	Number of polymorphic sites	NS sites	S sites	π (× 10⁻³)	k	θ	Tajima’s D	H	Hd
Myanmar	73	43	31	12	8.55	10.90	8.85	0.75	36	0.935
Sri Lanka	23	34	29	5	7.78	10.13	9.21	0.38	15	0.949
Papua New Guinea (Madang)	61	36	33	4	8.76	11.41	7.69	1.59	51	0.992
Papua New Guinea (East Sepik)	41	34	27	7	8.02	10.45	7.95	1.09	37	0.995
Thailand (Tak; 1996)	58	48	36	12	9.69	12.62	10.37	0.73	52	0.995
Thailand (Tak; 2007)	44	46	33	13	10.09	13.13	10.57	0.85	31	0.982
Thailand (Chantaburi)	56	44	34	10	10.02	13.04	9.58	1.22	25	0.895
India	10	27	22	5	8.31	10.82	9.54	0.64	7	0.911
South Korea	66	57	36	21	5.90	7.68	11.98	− 1.20	17	0.921
Venezuela	73	29	22	7	7.66	9.98	5.97	2.12*	17	0.908

n number of isolates, NS sites number of sites with non-synonymous nucleotide polymorphisms, S sites number of sites with synonymous nucleotide polymorphisms, π nucleotide diversity, k mean number of pairwise differences, θ Watterson’s theta, H number of haplotypes, Hd haplotype diversity
* p < 0.05, indicating rejection of the null hypothesis of a neutral mutation model (confidence limits from Tajima, 1989)

ISSN: 1475-2875