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Table 2 Residual parasite densities (estimated by ultrasensitive PCR quantitation) by treatment arm presented as a percentage relative to baseline density

From: Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

Time point

AL3

AL5

p value#

n/N

(Median; min–max)

n/N

(Median, min–max)

At 3 days

61/75

0.39 (0–2.72.17)

60/72

0.72 (0–133.48)

0.42

At 5 days

10/20

0.01 (0–82.13)

8/18

0 (0–0.40)

0.50

At 7 days

41/74

0.003 (0–7.00)

40/71

0.003 (0–6.72)

0.72

At 14 days

15/54

0 (0–0.04)

16/55

0 (0–0.44)

0.58

At 21 days

5/52

0 (0–0.01)

8/53

0 (0–0.48)

0.33

  1. N number of patients tested, n number positive
  2. Residual parasite density % calculation = 100 − [{(Parasite density day 0 − Parasite density day x)/Parasite density day 0} × 100]
  3. #Wilcoxon rank-sum (Mann–Whitney) test
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Malaria Journal

ISSN: 1475-2875

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