Fig. 6

Plasmodium falciparum invasion rates into red cells obtained from patients with varying total plasma cholesterol (TC) levels do not differ significantly. a Quantification of P. falciparum invasion rates into red cells from patients with low TC (< 5), elevated TC (> 5, < 10) and severely elevated TC (> 10). Values represent mean and standard deviation of triplicate wells. The invasion percentages summarized per group are shown for both experiments in b. The correlation between red cell invasion and total plasma cholesterol is shown in c along with the Pearson correlation coefficient (r), p value and a linear regression line modelling the correlation with 95% confidence intervals (CI). The correlation is not significant (p > 0.05). P values comparing P. falciparum invasion into red cells from low, elevated and highly elevated TC samples were calculated using the Student’s t test (ns not significant)