Fig. 3From: Protection induced by malaria virus-like particles containing codon-optimized AMA-1 of Plasmodium bergheiExperimental schedule and Plasmodium berghei-specific antibody responses upon immunization. Mice were immunized twice with VLPs, blood was collected, challenge infected and sacrificed as indicated in experimental schedule (a). P. berghei-specific IgG, IgG1, IgG2a and IgG2b antibody responses in the sera were determined after prime and boost (b–e, *P < 0.05). Data are expressed as mean ± SD. AMA-1 (O): non-codon optimized VLPs, AMA-1 (G): codon-optimized VLPsBack to article page