Fig. 4

Plasmodium berghei-specific antibodies responses upon challenge infection. Immunized mice were challenge-infected (IP) with P. berghei at week 4 after boost as indicated in the experimental schedule. P. berghei-specific IgG (a), IgG1 (b), IgG2a (c) and IgG2b (d) antibody responses in the sera were determined on day 10 post-challenge (a–d mean ± SD, *P < 0.05). Cha challenge infection. Data are expressed as mean ± SD