Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity

Table 3 IMGT/V-QUEST Allele analysis

Light chain	Gene segment	Allele	Score	Nt identity (%)	Identity (nt/nt)	Identity (aa/aa)
9	V-Gene	Homsap IGKV1-9*01 F	1237	93.91	262/279	82/94
9	J-Gene	Homsap IGKJ3*01 F	171	97.22	35/36	12/13
16	V-Gene	Homsap IGKV1-16*02 [F]	1264	94.62	264/279	83/94
16	J-Gene	Homsap IGKJ5*01 F	167	94.59	35/37	12/13
17	V-Gene	Homsap IGKV1-17*03 F	1372	99.28	277/279	93/94
17	J-Gene	Homsap IGKJ201 F, or Homsap IGKJ202 F	181	97.37	37/38	12/13
17B	V-Gene	Homsap IGKV1-17*03 F	1318	97.13	271/279	90/94
17B	J-Gene	Homsap IGKJ101 F, or Homsap IGKJ401 F	144	88.89	32/36	10/13

Germline alleles of V and J-genes were analysed using IMGT/V-QEST for the analysis of human immunoglobulin (IG) or antibody nucleotide sequences. The V- and J-gene alleles with the closest identity to the AMA1-specific light chains are listed. The identity of the phage display derived light chains with their closest germline allele is given as percentage and as number of nucleotides per total nucleotides (nt)

ISSN: 1475-2875