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Fig. 4 | Malaria Journal

Fig. 4

From: Hepatic safety of repeated treatment with pyronaridine‐artesunate versus artemether–lumefantrine in patients with uncomplicated malaria: a secondary analysis of the WANECAM 1 data from Bobo-Dioulasso, Burkina Faso

Fig. 4

Total bilirubin over ALT and AST by episode groups and treatment arms. The horizontal solid lines represent a total bilirubin level of 2 times the upper limit of normal range (ULN) and the vertical dotted lines correspond to a transaminase level of 3 times the ULN giving a four quadrants distribution of the study participants’ liver enzymes. Participants with isolated hyperbilirubinemia are represented in the top left quandrant and those fulfulling criteria of Hy’s law are in the top right quandrants. Participants with isolated liver injury are spotted in the bottom right quandrants and the bottom left shows study participants whithin the normal range

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