Fig. 1
From: Anti‐malarial drug effects on parasite dynamics in vivax malaria
The temporal distribution of first relapses in tropical P. vivax infections treated with different anti-malarial drugs. Artesunate was given for 5 or 7 days. The quinine interval was derived from studies in which quinine was given for 14 days. The interval is shorter after currently recommended 7-day quinine regimens. The other drugs are given in 3 day regimens. Lumefantrine and piperaquine are the slowly eliminated components of artemisinin-based combinations. This temporal pattern of first relapses reflects the elimination kinetics of the different drugs and thus the duration of suppression of asexual stage multiplication in the relapsing infection [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28]