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Table 1 Effect of PMCA4 inhibition on parasite count at 48 h after initiation of culture

From: Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo

Drug concentration (M)

Parasite count at 48 h, %

Artemisinin

ATA

Resveratrol

 

(1*)

(2)

(1)

(2)

(1)

(2)

10–10 (Untreated)

6.4

4.7

4.2

3.1

9

17

10–9

2.3

2.1

15

8

10–8

2.1

1.6

12

11

10–7

0

0

3.3

2.8

1.8

1.2

10–6

0

0

3.9

2.7

0.7

1.3

10–5

0

0

3.4

3.3

0.7

1.3

10–4

0

0

0.8

1

1.4

1.6

10–3

0

0

0

0

0.9

0.8

  1. * = assay 1