Variability in white blood cell count during uncomplicated malaria and implications for parasite density estimation: a WorldWide Antimalarial Resistance Network individual patient data meta-analysis

Table 2 Summary of day0 WBC count in patients with malaria, by Plasmodium species

Parameter	Plasmodium falciparum		Plasmodium vivax
Parameter	N	Geometric Mean [min; max] or n [%]	N	Geometric Mean [min; max] or n [%]
WBC count (/μL)
All age groups	24978	7300 [200; 87000]	2678	6200 [1200; 29400]
< 1 year	1044	10500 [1800; 48580]	2	7500 [7100; 8000]
1–4 years	11606	8300 [1000; 85000]	168	7000[2900; 22400]
5–14 years	5797	7100 [900; 78000]	501	6500[2000; 25700]
15 + years	6531	5700 [200; 87000]	2007	6000 [1200; 29400]
Leukocytosis	24978	1100 [4.4]	2678	41 [1.5]
Leukopenia	24978	3607 [14.4]	2678	277 [10.3]
Clinical Leukopenia (DAIDS grading)	24978	251 [1.0]	2678	27 [1.0]
Mild		153 [0.6]		23 [0.9]
Moderate		54 [0.2]		2 [0.1]
Severe		40 [0.2]		2 [0.1]
Life threatening		4 [0.02]		0 [0.0]

ISSN: 1475-2875