Table 2 Observed major Raman bands [cm⁻¹] and their assignments for single human RBC: healthy, P. falciparum and P. vivax infected excited using 514.5 nm laser line

2930

2929/2932

2931/2932

ν_sym(CH₃); PC

symmetrical CH stretching vibration of CH₃

[8,9,10, 23]

1639

1638/1639

1637/1638

haem; ν₁₀; amide I (conf. α)

ν(C_αC_m)_as

ν(C = O), ν(CN) and δ(NH)

[8,9,10, 15, 23]

1586

1586/1587

1585/1586

haem; ν₃₇; Asp;

His;

ν(C_αC_m)_as; phenyl mode ν _as(COO⁻);

ν(C₄ = C₅),

[8,9,10, 15, 22, 24, 28]

1372

1359/1372

1360/1371

haem; ν₄;

Trp

ν(C_αC_m)_as

W7

[8,9,10, 15, 22, 28]

1170

1171/1170

1170/1169

haem (Hz); ν_30;

Asp, Glu;

Tyr; ν_9a

_pyr(half-ring)_as

ν(CO);

ν(CH); δ(COH)

[8,9,10, 15, 22, 23, 34]

1125

1128/1127

1127/1126

haem; ν_22;

Asp, Glu;

ν_pyr (half-ring)_as;

ν(CO);

[8,9,10, 15, 22, 36]

1002

1001/1002

1000/1001

haem (Hz); ν₄₅;

Phe

ν(C_β -methyl);

ν(CC), ring breathing;

[8,9,10, 15, 22, 23]

745

746/751

745/753

haem; ν₁₅

Thr

ν(pyr. breathing) γ_rock(CH₂)

[8,9,10, 15, 23, 31]