Anti-malarial activity of the alkaloid, heptaphylline, and the furanocoumarin, imperatorin, from Clausena anisata against human Plasmodium falciparum malaria parasites: ex vivo trophozoitocidal, schizonticidal and gametocytocidal approach

Table 1 The IC₅₀ (SD) of the compounds on the inhibition of the various stages of P. falciparum

Compound	Trophozoite schizont gametocyte
Compound	IC₅₀/µM	IC₅₀/µM	IC₅₀/µM
Imperatorin	1.57 (0.2317)	8.97 (0.8935)	26.92 (0.3144)
Heptaphylline	2.23 (0.0801)	6.71 (1.0094)	20.87 (0.1762)
Artesunate	0.00024 (0.0036)	0.0070 (0.0013)	0.00024 (0.00004)

ISSN: 1475-2875