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Table 2 CC50 and SI of the compounds against the various stages of human P. falciparum

From: Anti-malarial activity of the alkaloid, heptaphylline, and the furanocoumarin, imperatorin, from Clausena anisata against human Plasmodium falciparum malaria parasites: ex vivo trophozoitocidal, schizonticidal and gametocytocidal approach

Compound

CC50/µM

SI of the compounds on various stages of human P. falciparum

Trophozoite

Schizont

Gametocyte

Imperatorin

370.37

235.90

41.28

13.76

Heptaphylline

358.42

160.73

53.41

17.17

Artesunate

Nd

Nd

Nd

Nd

  1. Nd not determined