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Fig. 5 | Malaria Journal

Fig. 5

From: Human monoclonal antibodies inhibit invasion of transgenic Plasmodium knowlesi expressing Plasmodium vivax Duffy binding protein

Fig. 5

Invasion inhibition with combination of humAb 099100 with humAbs DB9, DB10 and DB42: A, C, E Growth inhibition curves for humAbs DB9, DB10, DB42, and 099100 individually, with and without the presence of 099100 held constant at its IC25 (50 µg/mL, green dot). All points represent mean and standard deviation with triplicate cultures. B, D, F 3-dimensional representations of the dose–response matrices showing varying concentrations of DB9 (B), DB10 (D), and DB42 (F) on the x-axis, respectively from top to bottom, 099100 on the y-axis, and synergy score (δ) on the z-axis. Refer to legend in Fig. 3 describing Bliss synergy matrix and scores

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Malaria Journal

ISSN: 1475-2875

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