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Table 1 Time to detection of blood stage parasites after challenge of pig-tailed macaques with infectious P. knowlesi sporozoites (PkSPZ)

From: Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research

 

Animal ID

Sex

PkSPZ challenge (days)

PkSPZ re-challenge (days)

18S rRNA RT-PCR

Thin blood smear

18S rRNA RT-PCR

Thin blood smear

Cohort 1

Z13228

M

7

11

No secondary challenge performed

Z16133

M

6

11

Z16318

M

6

11

Cohort 2

Z14235

F

6

11

6

–

Z16091

F

8

14

#

#

Z17137

M

6

13

6

–

Z18090

M

7

14

6

18*

Mean (days +/− SD)

6.6 +/− 0.8

12.1 +/− 1.5

6.0 +/− 0.0

18*

  1. Data by individual animal. # = this animal was not re-challenged due to recrudescent infection. * = transient patency by thin blood smear. M male; F female, SD standard deviation
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Malaria Journal

ISSN: 1475-2875

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