Fig. 5
Power curves for sample sizes 80 and 250 for VEHR and VEC. The calculations assume exponential time-to-event distributions, and the means and standard deviations of number of clones at first infection in each group match those in the RTS,S data. The black dots correspond to combinations of input parameters in Table 3. The analytic power estimates differ slightly from those in Table 3 because the RTS,S time-to-event distribution is not exponential, but they show the same general pattern