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Table 2 Different haplotype of Pfdhfr gene and their association with Pfdhps haplotypes (NIL: dhps gene didn’t successfully analysed and WILD TYPE: no mutations in the analysed samples)

From: Assessment of Plasmodium falciparum drug resistance associated molecular markers in Mandla, Madhya Pradesh, India

Pfdhfr

Pfdhps

Total

NIL

G437A

G437A, I514M

P444S, R569C

S436A

S436A, K540E

Wild type

C59R, S108N

 N

16

78

0

1

0

1

10

106

 %

15.10%

73.60%

0.00%

0.90%

0.00%

0.90%

9.40%

100.00%

L46S, C59R, S108N

 N

0

0

0

0

0

0

1

1

 %

0.00%

0.00%

0.00%

0.00%

0.00%

0.00%

100.00%

100.00%

N51I, C59R, S108N

 N

2

0

0

0

4

0

0

6

 %

33.30%

0.00%

0.00%

0.00%

66.70%

0.00%

0.00%

100.00%

S108N

 N

2

0

0

0

0

0

0

2

 %

100.00%

0.00%

0.00%

0.00%

0.00%

0.00%

0.00%

100.00%

Wild type

 N

11

70

0

0

0

0

3

84

 %

13.10%

83.30%

0.00%

0.00%

0.00%

0.00%

3.60%

100.00%

Total

 N

31

148

0

1

4

1

14

199

 %

15.58%

74.37

0.00%

0.50%

2.01%

0.50%

7.04%

100.00%