Table 1 Basic parameters of the study population
|  | HbAA (n = 72) | HbAC (n = 7) | HbAS (n = 19) | HbSC (n = 13) | HbSS (n = 23) |
|---|---|---|---|---|---|
Sexe ratio (M/F) | 1.1 | 2.5 | 0.4 | 0.5 | 1.6 |
Age (years), (Mean ± SD) | 12.90 ± 11.08 | 13.47 ± 10.67 | 12.43 ± 4.76 | 10.17 ± 4.42 | 19.15 ± 14.12 |
Body mass index (mean ± SD) | 20.65 ± 5.77 | 21.67 ± 4.54 | 19.06 ± 5.40 | 18.75 ± 4.22 | 14.41 ± 3.41 |
Temperature (°C), (mean ± SD) | 39.58 ± 1.16 | 39.87 ± 1.56 | 38.29 ± 0.92 | 38.28 ± 0.71 | 38.22 ± 1 .13 |
Parasitaemia (/µL of blood), Median (IQR) | 38315 (19515—53543) | 11200 (5610—57100) | 13670 (8220–42600) | 13,250 (4805–21800) | 16,300 (7900—43900) |
Leukocytes (× 1000/µL), (mean ± SD) | 17.57 ± 15.71 | 13.51 ± 13.07 | 16.80 ± 9.82 | 23.58 ± 22.68 | 17.83 ± 7.80 |
Erythrocytes (million/µL), (mean ± SD) | 4.65 ± 1.00 | 4.35 ± 0.99 | 3.44 ± 1.75 | 4.03 ± 1.79 | 2.48 ± 1.44 |
Platelets (× 1000/µL), (mean ± SD) | 233 ± 78.63 | 205.20 ± 88.80 | 282.10 ± 106.21 | 189.37 ± 79.92 | 261.47 ± 114.75 |
Haemoglobin level (G/100mL), (mean ± SD) | 11.28 ± 2.10 | 13.05 ± 2.53 | 8.66 ± 2.38 | 9.63 ± 1.71 | 6.51 ± 2.24 |
CRP, (mean ± SD) | 55.31 ± 50.29 | 65.86 ± 61.84 | 68.74 ± 52.39 | 66.31 ± 46.51 | 68. 35 ± 40.60 |
Haematocrit (%), (mean ± SD) | 38.64 ± 4. 60 | 43.55 ± 8.97 | 26.21 ± 7.88 | 27.15 ± 6.11 | 18.66 ± 6.71 |
p-Values | HbAA Vs HbAC | HbAA Vs HbAS | HbAA Vs HbSC | HbAA Vs HbSS |
|---|---|---|---|---|
Age (years) | 0.383 | 0.561 | 0.067 | 0.728 |
Body mass index | 0.677 | 0.359 | 0.262 |  < 0.001 |
Temperature (°C) | 0.678 |  < 0.001 |  < 0.001 |  < 0.001 |
Parasitaemia ( /µL of blood) | 0.061 | 0.012 |  < 0.001 | 0.014 |
Leukocytes (× 1000 / µL) | 0.616 |  < 0.001 | 0.248 | 0.054 |
Erythrocytes (million/µL) | 0.576 |  < 0.001 |  < 0.001 |  < 0.001 |
Platelets (× 1000/µL) | 0.228 | 0.086 | 0.218 | 0.277 |
Haemoglobin level (G/100mL | 0.083 |  < 0.001 | 0.218 |  < 0.001 |
CRP | 0.937 | 0.207 | 0.748 | 0.103 |
Haematocrit (%) | 0.196 |  < 0.001 |  < 0.001 |  < 0.001 |