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Table 2 Distribution of different haemoglobin phenotypes by age group

From: In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

 

HbAA (n = 72)

HbAS

HbAC

HbSS

HbSC

(n = 19)

(n = 7)

(n = 23)

(n = 13)

Mean age (years). [± SD]

12.90 ± 13

13.47 ± 10.67

12.43 ± 4.76

10.17 ± 4.42

19.15 ± 14.12

 < 5 yrs

N (%) Patients

29 (40.28%)

6 (31.58%)

0 (0%)

5 (21.74%)

2 (15.38%)

Mean age [± SD]

3.3 ± 1.44

3.33 ± 1.36

–

4.6 ± 0.55

4 ± 0.0

 > 5 yrs

N (%) Patients

43 (59.72%)

13 (68.42%)

7 (100%)

18 (78.26%)

11 (84.61%)

Mean age [± SD]

19.37 ± 13.33

18.15 ± 9.75

12.43 ± 4.76

11.72 ± 3.68

21.91 ± 13.60

P-Values

HbAA vs HbAS

HbAA vs HbAC

HbAA vs HbSS

HbAA vs HbSC

 > 5 yrs

Mean age

 

0.668

0.089

0.172

0.161

  1. N number of patients, HbSS homozygous pathological haemoglobin; HbSC double heterozygous pathological haemoglobin; HbAS and HbAC asymptomatic form; HbAA normal haemoglobin; SD standard deviation; yrs years