Fig. 1
From: Immunofluorescence study of cytoskeleton in endothelial cells induced with malaria sera
The alterations of actin filaments and ECs induced by malaria sera. A and E: Shrinkage of actin filaments and ECs with cortical condensation (asterisk- normal ECs, arrowheads- shrinkage); B and F: Appearance of eccentric nuclei (asterisks- normal ECs, arrowheads- eccentric nuclei); C and G: Presence of “spiking pattern” of actin filaments and EC membrane (arrowheads); D and H: Fragmentation and discontinuity of actin filaments and ECs (arrowheads). A–D: ECs induced by sera from complicated P. falciparum (magnification X200). ECs were incubated with media only (green line), non-malaria patient sera (grey line), malaria sera from P. vivax (orange line), uncomplicated P. falciparum (blue line) and complicated P. falciparum (red line). *Significant difference of complicated P. falciparum compared with all experimental groups (p < 0.05). **Significant difference of uncomplicated P. falciparum compared with all experimental groups (p < 0.05). Data are presented as mean ± SEM