Table 2 Independent association of demographic, clinical, and laboratory values with death in children with CM using blood lactate as a continuous independent variable

Age, months, mean (SD)

0.99

(0.99–1.00)

Sex, N (%)

 Male

1

(Ref)

1

(Ref)

 Female

1.37

(0.94–2.01)

1.72

(1.12–2.66)

Blantyre Coma Scale at admission, N (%)

 0

1

(Ref)

1

(Ref)

 1

0.53

(0.31–0.91)

0.71

(0.39–1.32)

 2

0.30

(0.17–0.53)

0.45

(0.24–0.84)

Parasite count, mean (SD), log (10)

1.28

(1.07–1.53)

Admission haematocrit %, mean (SD)

1.03

(1.00–1.05)

1.06

(1.03–1.05)

Admission white blood cell count, mean (SD)

1.04

(1.02–1.06)

1.02

(1.00-1.05)

Admission Lactate (mmol/L), mean (SD)

1.12

(1.07–1.16)

1.05

(0.99–1.11)

6 h Lactate (mmol/L), mean (SD)

1.20

(1.14–1.26)

1.16

(1.09–1.23)

Glucose (mmol/L), mean (SD)

1.01

(0.96–1.07)

Received blood transfusion, N (%)

1.18

(0.81–1.72)

 Received > 1 blood transfusion

3.38

(1.62–7.05)

Received crystalloid bolus, N (%)

3.29

(2.22–4.87)

1.80

(1.07–3.03)

 Received > 1 bolus

3.38

(1.62–7.05)