Table 3 Independent association of demographic, clinical, and laboratory values with death in children with CM when blood lactate values are dichotomized
Univariate | Backwards selection (P-stay < 0.1) | |||
|---|---|---|---|---|
OR | 95% CI | OR | 95% CI | |
Age, months, mean (SD) | 0.99 | (0.99–1.00) | ||
Sex, N (%) | ||||
Male | 1 | (Ref) | 1 | (Ref) |
Female | 1.37 | (0.94–2.01) | 1.63 | (1.07–2.48) |
Blantyre Coma Scale at admission, N (%) | ||||
0 | 1 | (Ref) | 1 | (Ref) |
1 | 0.53 | (0.31–0.91) | 0.67 | (0.37–1.21) |
2 | 0.30 | (0.17–0.53) | 0.42 | (0.23–0.77) |
Parasite count, mean (SD), log (10) | 1.28 | (1.07–1.53) | ||
Admission haematocrit %, mean (SD) | 1.03 | (1.00-1.05) | 1.04 | (1.01–1.07) |
Admission white blood cell count, mean (SD) | 1.04 | (1.02–1.06) | 1.03 | (1.01–1.05) |
Admission hyperlactataemia | 2.95 | (1.94–4.50) | 2.49 | (1.47–4.22) |
6-Hour hyperlactataemia | 0.99 | (0.46–2.12) | 2.20 | (0.91–5.32) |
Glucose (mmol/L), mean (SD) | 1.01 | (0.96–1.07) | ||
Received blood transfusion, N (%) | 1.18 | (0.81–1.72) | ||
Received > 1 blood transfusion | 3.38 | (1.62–7.05) | ||
Received crystalloid bolus, N (%) | 3.29 | (2.22–4.87) | 2.40 | (1.52–3.79) |
Received > 1 bolus | 3.38 | (1.62–7.05) | ||