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Table 3 pfmdr1 mutations among samples collected in the eight regions from 2016 to 2021

From: Trends of Plasmodium falciparum molecular markers associated with resistance to artemisinins and reduced susceptibility to lumefantrine in Mainland Tanzania from 2016 to 2021

Year

Region

#Sequenced

pfmdr1* R1, n (%)

N86, n (%)

Y184, n (%)

184F n (%)

pfmdr1* R2, n (%)

D1246 n (%)

1246Y n (%)

2016

Kigoma

118

118 (100.0)

118 (100.0)

78 (66.1)

40 (33.9)

118 (100.0)

118 (100.0)

0 (0.0)

Morogoro

104

104 (100.0)

104 (100.0)

67 (64.4)

37 (35.6)

104 (100.0)

103 (99.0)

1 (1.0)

Pwani

92

92 (100.0)

92 (100.0)

51 (55.4)

41 (44.6)

92 (100.0)

92 (100.0)

0 (0.0)

Tanga

109

109 (100.0)

109 (100.0)

62 (56.9)

47 (43.1)

109 (100.0)

108 (99.1)

1 (0.9)

2018

Kigoma

111

110 (99.1)

110 (99.1)

76 (69.1)

34 (30.9)

104 (93.7)

104 (100.0)

0 (0.0)

Morogoro

99

94 (94.9)

94 (94.9)

69 (73.4)

25 (26.6)

86 (86.9)

86 (100.0)

0 (0.0)

Pwani

97

86 (88.7)

86 (88.7)

53 (61.6)

33 (38.4)

87 (89.7)

87 (100.0)

0 (0.0)

Tanga

119

111 (93.3)

111 (93.3)

56 (50.5)

55 (49.5)

102 (85.7)

102 (100.0)

0 (0.0)

2019

Mbeya

95

88 (92.6)

88 (92.6)

48 (54.5)

40 (45.5)

84 (88.4)

84 (100.0)

0 (0.0)

Mtwara

93

89 (95.7)

89 (95.7)

56 (62.9)

33 (37.1)

89 (95.7)

89 (100.0)

0 (0.0)

Tabora

111

98 (88.3)

98 (88.3)

68 (69.4)

30 (30.6)

97 (87.4)

97 (100.0)

0 (0.0)

Mwanza

104

96 (92.3)

96 (92.3)

67 (69.8)

29 (30.2)

102 (98.1)

102 (100.0)

0 (0.0)

2020

Pwani

97

90 (92.8)

90 (92.8)

38 (42.2)

53 (58.9)

79 (81.4)

79 (100 .0)

0 (0.0)

Kigoma

103

92 (89.3)

92 (89.3)

61 (66.3)

31 (33.7)

65 (63.1)

64 (98.5)

1 (1.5)

Morogoro

96

91 (94.8)

91 (94.8)

54 (59.3)

39 (42.9)

85 (88.5)

84 (98.8)

1 (1.2)

Tanga

116

105 (90.5)

105 (90.5)

51 (48.6)

55 (52.4)

101 (87.1)

101 (100.0)

0 (0.0)

2021

Mbeya

48

35 (72.9)

35 (72.9)

17 (48.6)

18 (51.4)

34 (70.8)

34 (100.0)

0 (0.0)

Mtwara

87

86 (98.9)

86 (98.9)

34 (39.5)

52 (60.5)

65 (74.7)

65 (100.0)

0 (0.0)

Mwanza

106

105 (99.1)

105 (99.1)

44 (41.9)

61 (58.1)

94 (88.7)

94 (100.0)

0 (0.0)

Tabora

110

109 (99.1)

109 (99.1)

59 (54.1)

50 (45.9)

77 (70.0)

77 (100.0)

0 (0.0)

Total

 

2015

1908 (94.7)

1906 (99.9)

1109 (58.1)

803 (42.0)

1774 (88.0)

1770 (99.0)

4 (0.2)

  1. *number of samples which passed the sequencing quality score criteria, n = number of samples. % = percentage of samples analyzed or with a particular genotype