Table 4 Haemoglobin increase (compared to Hb D0) during the follow period among children treated with artemether-lumefantrine (AL) or dihydroartemisinin-piperaquine (DP) at Kouvé and Anié. Togo. 2021–2022

AL^a

 Anié

Mean increase

0.29

0.88

1.02

1.22

1.23

1.31

95% CI

0.03–0.55

0.58–1.19

0.72–1.32

0.90–1.53

0.90–1.57

0.95 to 1.67

P-value

 < 0.04

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 Kouvé

Mean increase

0.05914

0.91

1.4811

1.71

1.74

1.84

95% CI

− 0.21 to 0.33

0.60 to 1.23

1.12 to 1.84

1.33 to 2.09

1.36 to 2.14

1.44 to 2.24

P-value

0.66

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

DP^b

 Anié

Mean increase

0.46

1.14

1.57

1.65

1.76

1.82

95% CI

0.10 to 0.81

0.80 to 1.48

1.22 to 1.93

1.27 to 2.04

1.36 to 2.15

1.46 to 2.18

P-value

 < 0.02

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001

 Kouvé

Mean decrease

− 0.3284

0.58

1.18

1.51

1.62

1.74

95% CI

− 0.59 to − 0.07

0.23 to 0.93

0.23 to 0.93

1.16 to 1.86

1.25 to 1.98

1.25 to 1.98

P-value

 < 0.02

 < 0.002

 < 0.0001

 < 0.0001

 < 0.0001

 < 0.0001