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Suppression of erythropoiesis by Plasmodium vivax infection
© Panichakul et al; licensee BioMed Central Ltd. 2010
- Published: 20 October 2010
- Cord Blood
- Severe Anemia
The reduction of erythroid expansion was not significantly greater by intact PV-IE when compared with lysed PV-IE. The inhibition of cell expressing glyphorin A was up to 66.67 % compared with controls.
P. vivax could inhibit erythroid growth and development and this suppression of erythropoiesis by P. vivax infection is plausible to involve in induction of anemia.
This was supported by Thailand research fund, Commission on Higher Education, Ministry of Education and Suan Dusit Rajabhat University, Bangkok, Thailand (MRG5380092).
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