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  1. Malaria volunteers have contributed significantly to malaria control achieving a reduction of annual parasite incidence to pre-elimination levels in several townships across Myanmar. However, the volunteers’ r...

    Authors: Win Han Oo, Elizabeth Hoban, Lisa Gold, Kyu Kyu Than, Thazin La, Aung Thi and Freya J. I. Fowkes

    Citation: Malaria Journal 2021 20:19

    Content type: Research

    Published on:

  2. Accurate measurement of anti-malarial drug concentrations in therapeutic efficacy studies is essential to distinguish between inadequate drug exposure and anti-malarial drug resistance, and to inform optimal a...

    Authors: Thomas A. Anyorigiya, Sandra Castel, Katya Mauff, Frank Atuguba, Bernhards Ogutu, Abraham Oduro, David Dosoo, Kwaku-Poku Asante, Seth Owusu-Agyei, Alexander Dodoo, Abraham Hodgson, Fred Binka, Lesley J. Workman, Elizabeth N. Allen, Paolo Denti, Lubbe Wiesner…

    Citation: Malaria Journal 2021 20:18

    Content type: Research

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    The Correction to this article has been published in Malaria Journal 2021 20:156

  3. Elevated angiopoietin-2 (Angpt-2) concentrations are associated with worse overall neurocognitive function in severe malaria survivors, but the specific domains affected have not been elucidated.

    Authors: Benson J. Ouma, Paul Bangirana, John M. Ssenkusu, Dibyadyuti Datta, Robert O. Opoka, Richard Idro, Kevin C. Kain, Chandy C. John and Andrea L. Conroy

    Citation: Malaria Journal 2021 20:17

    Content type: Research

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  4. Although autochthonous malaria cases are no longer reported in Anhui Province, China, imported malaria has become a major health concern. The proportion of reported malaria cases caused by Plasmodium ovale spp. i...

    Authors: Tao Zhang, Shuqi Wang, Duoquan Wang, Sarah Auburn, Shenning Lu, Xian Xu, Jingjing Jiang, Xiaofeng Lyu, Chen Yu, Cuicui Tian, Shizhu Li and Weidong Li

    Citation: Malaria Journal 2021 20:15

    Content type: Research

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  5. Microscopy and rapid diagnostic tests (RDTs) are the main techniques used to diagnose malaria. While microscopy is considered the gold standard, RDTs have established popularity as they allow for rapid diagnos...

    Authors: Nobert Mudare, Zvifadzo Matsena-Zingoni, Aramu Makuwaza, Edmore Mamini, Shungu S. Munyati, Lovemore Gwanzura, Nicholas Midzi, Susan L. Mutambu, Peter Mason, Tamaki Kobayashi and Sungano Mharakurwa

    Citation: Malaria Journal 2021 20:14

    Content type: Research

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  6. Malaria and HIV are two important public health issues. However, evidence on HIV-Plasmodium vivax co-infection (HIV/PvCo) is scarce, with most of the available information related to Plasmodium falciparum on the ...

    Authors: Paola López Del-Tejo, Nadia Cubas-Vega, Cecilia Caraballo-Guerra, Bernardo Maia da Silva, Jefferson da Silva Valente, Vanderson Souza Sampaio, Djane Clarys Baia-da-Silva, Daniel Barros Castro, Flor Ernestina Martinez-Espinosa, André Machado Siqueira, Marcus Vinícius Guimarães Lacerda, Wuelton Marcelo Monteiro and Fernando Val

    Citation: Malaria Journal 2021 20:13

    Content type: Research

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  7. N,N-Diethyl-3-methylbenzamide (DEET) topical mosquito repellents are effective personal protection tools. However, DEET-based repellents tend to have low consumer acceptability because they are cosmetically unapp...

    Authors: Emmanuel Mbuba, Olukayode G. Odufuwa, Frank C. Tenywa, Rose Philipo, Mgeni M. Tambwe, Johnson K. Swai, Jason D. Moore and Sarah J. Moore

    Citation: Malaria Journal 2021 20:12

    Content type: Research

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  8. The invasion of the mosquito salivary glands by Plasmodium sporozoites is a critical step that defines the success of malaria transmission and a detailed understanding of the molecules responsible for salivary gl...

    Authors: Bianca B. Kojin, Ines Martin-Martin, Helena R. C. Araújo, Brian Bonilla, Alvaro Molina-Cruz, Eric Calvo, Margareth L. Capurro and Zach N. Adelman

    Citation: Malaria Journal 2021 20:11

    Content type: Research

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  9. Plasmodium falciparum causes the majority of malaria cases worldwide and children in sub-Saharan Africa are the most vulnerable group affected. Non-sterile clinical immunity that protects from symptoms develops s...

    Authors: Triniti C. Turner, Charles Arama, Aissata Ongoiba, Safiatou Doumbo, Didier Doumtabé, Kassoum Kayentao, Jeff Skinner, Shanping Li, Boubacar Traore, Peter D. Crompton and Anton Götz

    Citation: Malaria Journal 2021 20:9

    Content type: Research

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  10. It is frequently said that funding is essential to ensure optimal results from a malaria intervention control. However, in recent years, the capacity of the government of Mozambique to sustain the operational ...

    Authors: Neide Canana

    Citation: Malaria Journal 2021 20:8

    Content type: Research

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  11. Malaria is known as a disease of poverty because of its dominance in poverty-stricken areas. Madhya Pradesh state in central India is one of the most vulnerable states for malaria morbidity and mortality. Soci...

    Authors: Ravendra K. Sharma, Harsh Rajvanshi, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal

    Citation: Malaria Journal 2021 20:7

    Content type: Research

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  12. Consistent use of insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp) have been recommended as cost-effective interventions for malaria prevention during pregnancy in ende...

    Authors: Solomon Tsebeni Wafula, Hilbert Mendoza, Aisha Nalugya, David Musoke and Peter Waiswa

    Citation: Malaria Journal 2021 20:5

    Content type: Research

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  13. Rapid diagnostic tests (RDTs) play a key role in malaria case management. The most widely used RDT identifies Plasmodium falciparum based on immunochromatographic recognition of P. falciparum histidine-rich prote...

    Authors: Sam L. Nsobya, Andrew Walakira, Elizabeth Namirembe, Moses Kiggundu, Joaniter I. Nankabirwa, Emmanuel Ruhamyankaka, Emmanuel Arinaitwe, Melissa D. Conrad, Moses R. Kamya, Grant Dorsey and Philip J. Rosenthal

    Citation: Malaria Journal 2021 20:4

    Content type: Research

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  14. Kniphofia foliosa is a flamboyant robust perennial herb which has dense clumps and tick upright rhizomes with leaves at the base. In Ethiopia, it has several vernacular names including Abelbila, Ashenda, Amelmela

    Authors: Yonatan Alebachew, Daniel Bisrat, Solomon Tadesse and Kaleab Asres

    Citation: Malaria Journal 2021 20:3

    Content type: Research

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  15. There is a global consensus that new intervention tools are needed for the final steps toward malaria elimination/eradication. In a recent study in Burkina Faso, the Lehmann Funnel Entry Trap (LFET) has shown ...

    Authors: Roger Sanou, Hamidou Maïga, Etienne M. Bilgo, Simon P. Sawadogo, Bazoumana B. D. Sow, Adama Ouema, Koama Bayili, Adrien Marie Gaston Belem, Léa Paré Toé, Roch K. Dabiré and Abdoulaye Diabaté

    Citation: Malaria Journal 2021 20:2

    Content type: Research

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  16. In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strat...

    Authors: Lamine Mahaman Moustapha, Rafiou Adamou, Maman Laminou Ibrahim, Mariama Abdoulaye Louis Padounou, Abdoulaye Diallo, David Courtin, Jean Testa and Jean Louis Abdourahim Ndiaye

    Citation: Malaria Journal 2021 20:1

    Content type: Research

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  17. While the World Health Organization (WHO) Southeast Asia region has the second highest incidence of malaria worldwide, malaria in Vietnam is focal to few provinces, where delayed parasite clearance to anti-mal...

    Authors: Bui Van Long, Genevieve Allen, Melanie Brauny, Le Thi Kieu Linh, Srinivas Reddy Pallerla, Tran Thi Thu Huyen, Hoang Van Tong, Nguyen Linh Toan, Do Quyet, Ho Anh Son and Thirumalaisamy P. Velavan

    Citation: Malaria Journal 2020 19:458

    Content type: Research

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  18. The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African cou...

    Authors: Mogahed Ismail Hassan Hussein, Ahmed Abdalazim Dafallah Albashir, Omer Ali Mohamed Ahmed Elawad and Anmar Homeida

    Citation: Malaria Journal 2020 19:457

    Content type: Review

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  19. Understanding the molecular basis of insecticide resistance in mosquito, such as Anopheles funestus, is an important step in developing strategies to mitigate the resistance problem. This study aims to assess the...

    Authors: Genevieve M. Tchigossou, Seun M. Atoyebi, Romaric Akoton, Eric Tossou, Djegbe Innocent, Jacob Riveron, Helen Irving, Akadiri Yessoufou, Charles Wondji and Rousseau Djouaka

    Citation: Malaria Journal 2020 19:456

    Content type: Research

    Published on:

  20. Malaria in pregnancy remains a major contributor to maternal and infant morbidity and mortality despite scale up in interventions. Its prevention is one of the major interventions in reducing maternal and infa...

    Authors: Maria Imaobong Ibegu, Khadeejah Liman Hamza, Chukwuma David Umeokonkwo, Tamuno-Wari Numbere, Adolphe Ndoreraho and Tukur Dahiru

    Citation: Malaria Journal 2020 19:455

    Content type: Research

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  21. Pyrethroid-treated mosquito nets are currently the mainstay of vector control in Côte d’Ivoire. However, resistance to pyrethroids has been reported across the country, limiting options for insecticide resista...

    Authors: Bernard L. Kouassi, Constant Edi, Emmanuel Tia, Lucien Y. Konan, Maurice A. Akré, Alphonsine A. Koffi, Allassane F. Ouattara, Antoine Mea Tanoh, Pascal Zinzindohoue, Blaise Kouadio, McKenzie Andre, Seth R. Irish, Jennifer Armistead, Dereje Dengela, Ndombour G. Cissé, Cecilia Flatley…

    Citation: Malaria Journal 2020 19:454

    Content type: Research

    Published on:

  22. In clinical trials of therapy for uncomplicated Plasmodium falciparum, there are usually some patients who fail treatment even in the absence of drug resistance. Treatment failures, which can be due to recrudesce...

    Authors: Rida Mumtaz, Lucy C. Okell and Joseph D. Challenger

    Citation: Malaria Journal 2020 19:453

    Content type: Research

    Published on:

  23. Prevention of re-establishment (POR) refers to the prevention of malaria outbreak/epidemic occurrence or preventing re-establishment of indigenous malaria in a malaria-free country. Understanding the effective...

    Authors: S. M. Ibraheem Nasir, Sachini Amarasekara, Renu Wickremasinghe, Deepika Fernando and Preethi Udagama

    Citation: Malaria Journal 2020 19:452

    Content type: Review

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  24. An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of t...

    Authors: Beatriz Galatas, Alfredo Mayor, Himanshu Gupta, Núria Balanza, Ihn Kyung Jang, Lidia Nhamussua, Wilson Simone, Pau Cisteró, Arlindo Chidimatembue, Humberto Munguambe, Francisco Saúte, Pedro Aide and Quique Bassat

    Citation: Malaria Journal 2020 19:451

    Content type: Research

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  25. The high incidence of Plasmodium vivax infections associated with clinical severity and the emergence of chloroquine (CQ) resistance has posed a challenge to control efforts aimed at eliminating this disease. Des...

    Authors: Fredy E. Villena, Jorge L. Maguiña, Meddly L. Santolalla, Edwar Pozo, Carola J. Salas, Julia S. Ampuero, Andres G. Lescano, Danett K. Bishop and Hugo O. Valdivia

    Citation: Malaria Journal 2020 19:450

    Content type: Research

    Published on:

  26. Placental malaria (PM) has been associated with a higher risk of malaria during infancy. However, it is unclear whether this association is causal, and is modified by infant sex, and whether intermittent preve...

    Authors: Abel Kakuru, Michelle E. Roh, Richard Kajubi, Teddy Ochieng, John Ategeka, Harriet Ochokoru, Miriam Nakalembe, Tamara D. Clark, Theodore Ruel, Sarah G. Staedke, Daniel Chandramohan, Diane V. Havlir, Moses R. Kamya, Grant Dorsey and Prasanna Jagannathan

    Citation: Malaria Journal 2020 19:449

    Content type: Research

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  27. Malaria has been one of the commonest diseases during farming season, which affects farmers’ health resulting in a reduction in the number of days spent on the farm. As a result, farmers are regularly trying t...

    Authors: Franklin Nantui Mabe and Thomas Dafurika

    Citation: Malaria Journal 2020 19:448

    Content type: Research

    Published on:

  28. Understanding of malaria vector density, distribution, insecticide resistance, vector incrimination, infection status, and identification of sibling species are some of the essential components of vector contr...

    Authors: Ashok K. Mishra, Praveen K. Bharti, Anup Vishwakarma, Sekh Nisar, Harsh Rajvanshi, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Himanshu Jayswar, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal

    Citation: Malaria Journal 2020 19:447

    Content type: Research

    Published on:

  29. Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine–pyrimethamine (AS + SP)...

    Authors: Aymen M. Madkhali, Hesham M. Al-Mekhlafi, Wahib M. Atroosh, Ahmad Hassn Ghzwani, Khalid Ammash Zain, Ahmed A. Abdulhaq, Khalid Y. Ghailan, Alkhansa A. Anwar and Zaki M. Eisa

    Citation: Malaria Journal 2020 19:446

    Content type: Research

    Published on:

  30. Accurate measures of malaria incidence are essential to track progress and target high-risk populations. While health management information system (HMIS) data provide counts of malaria cases, quantifying the ...

    Authors: Adrienne Epstein, Jane Frances Namuganga, Emmanuel Victor Kamya, Joaniter I. Nankabirwa, Samir Bhatt, Isabel Rodriguez-Barraquer, Sarah G. Staedke, Moses R. Kamya, Grant Dorsey and Bryan Greenhouse

    Citation: Malaria Journal 2020 19:445

    Content type: Research

    Published on:

  31. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ruben O. Conner, Yakou Dieye, Michael Hainsworth, Adama Tall, Badara Cissé, Farba Faye, Mame Demba Sy, Amadou Ba, Doudou Sene, Souleymane Ba, Elhadji Doucouré, Tidiane Thiam, Moussa Diop, Kammerle Schneider, Moustapha Cissé, Mady Ba…

    Citation: Malaria Journal 2020 19:443

    Content type: Correction

    Published on:

    The original article was published in Malaria Journal 2020 19:252

  32. Plasmodial transketolase (PTKT) enzyme is one of the novel pharmacological targets being explored as potential anti-malarial drug target due to its functional role and low sequence identity to the human enzyme...

    Authors: Rita Afriyie Boateng, Özlem Tastan Bishop and Thommas Mutemi Musyoka

    Citation: Malaria Journal 2020 19:442

    Content type: Research

    Published on:

  33. Following a dramatic decline of malaria cases in Aceh province, geographically-based reactive case detection (RACD) was recently evaluated as a tool to improve surveillance with the goal of malaria elimination...

    Authors: Lenny L. Ekawati, Kelly C. Johnson, Jerry O. Jacobson, Carmen A. Cueto, Iska Zarlinda, Iqbal R. F. Elyazar, Abdul Fatah, Maria E. Sumiwi, Rintis Noviyanti, Chris Cotter, Jennifer L. Smith, Farah N. Coutrier and Adam Bennett

    Citation: Malaria Journal 2020 19:441

    Content type: Research

    Published on:

  34. Cryptic Plasmodium niches outside the liver possibly represent a major source of hypnozoite-unrelated recrudescences in malaria. Maurizio Ascoli, an Italian physician and scientist, suggested that infection was m...

    Authors: Wuelton Monteiro, José Diego Brito-Sousa, Aleix Elizalde-Torrent, Camila Bôtto-Menezes, Gisely Cardoso Melo, Carmen Fernandez-Becerra, Marcus Lacerda and Hernando A. del Portillo

    Citation: Malaria Journal 2020 19:440

    Content type: Review

    Published on:

  35. The analysis of single nucleotide polymorphism (SNPs) in drug-resistance associated genes is a commonly used strategy for the surveillance of anti-malarial drug resistance in populations of parasites. The pres...

    Authors: Auwal Adamu, Mahmoud Suleiman Jada, Hauwa Mohammed Sani Haruna, Bassa Obed Yakubu, Mohammed Auwal Ibrahim, Emmanuel Oluwadare Balogun, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Kenji Hirayama, Richard Culleton and Mohammed Nasir Shuaibu

    Citation: Malaria Journal 2020 19:439

    Content type: Research

    Published on:

  36. In areas of high transmission, malaria in pregnancy (MiP) primarily causes asymptomatic infections; these infections nonetheless increase the risk of adverse maternal and fetal outcomes. In 2014, Tanzania init...

    Authors: Chonge Kitojo, Frank Chacky, Emmanuel S. Kigadye, Joseph P. Mugasa, Abdallah Lusasi, Ally Mohamed, Patrick Walker, Erik J. Reaves, Julie R. Gutman and Deus S. Ishengoma

    Citation: Malaria Journal 2020 19:438

    Content type: Research

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  37. Extensive genetic diversity in the Plasmodium falciparum circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of...

    Authors: Elikplim A. Amegashie, Lucas Amenga-Etego, Courage Adobor, Peter Ogoti, Kevin Mbogo, Alfred Amambua-Ngwa and Anita Ghansah

    Citation: Malaria Journal 2020 19:437

    Content type: Research

    Published on:

  38. Larval source management is recommended as a supplementary vector control measure for the prevention of malaria. Among the concerns related to larviciding is the feasibility of implementation in tropical areas...

    Authors: John E. Gimnig, Maurice Ombok, Nabie Bayoh, Derrick Mathias, Eric Ochomo, William Jany and Edward D. Walker

    Citation: Malaria Journal 2020 19:436

    Content type: Research

    Published on:

  39. Anti-malarial drug resistance is a severe challenge for eventual control and global elimination of malaria. Resistance to sulfadoxine-pyrimethamine (SP) increases as mutations accumulate in the Pfdhfr and Pfdhps ...

    Authors: Tingting Jiang, Weijia Cheng, Yi Yao, Huabing Tan, Kai Wu and Jian Li

    Citation: Malaria Journal 2020 19:434

    Content type: Research

    Published on:

  40. Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for preventing malaria in pregnancy in areas of moderate-to-high transmission in sub-Saharan Africa. How...

    Authors: Jenny Hill, Peter Ouma, Seth Oluoch, Jane Bruce, Simon Kariuki, Meghna Desai and Jayne Webster

    Citation: Malaria Journal 2020 19:433

    Content type: Research

    Published on:

  41. In 2020, Benin has implemented a digitalized mass distribution campaign of insecticide-treated nets (ITNs) in the particular context of COVID-19 pandemic. This paper describes the implementation process as wel...

    Authors: Rock Aïkpon, Cyriaque Affoukou, Benjamin Hounpkatin, Dieu-Donné Eclou, Yves Cyaka, Elijah Egwu, Narcisse Agbessi, Filémon Tokponnon, Sahidou Salifou, Lamidhi Salami and Aurore Ogouyemi Hounto

    Citation: Malaria Journal 2020 19:431

    Content type: Research

    Published on:

  42. Automated detection of malaria and dengue infection has been actively researched for more than two decades. Although many improvements have been achieved, these solutions remain too expensive for most laborato...

    Authors: Parag Dharap and Sebastien Raimbault

    Citation: Malaria Journal 2020 19:429

    Content type: Methodology

    Published on:

  43. Well-defined promoters are essential elements for genetic studies in all organisms, and enable controlled expression of endogenous genes, transgene expression, and gene editing. Despite this, there is a paucit...

    Authors: Laura M. Bowman, Logan E. Finger, Kevin J. Hart and Scott E. Lindner

    Citation: Malaria Journal 2020 19:424

    Content type: Research

    Published on:

  44. Solving the problem of malaria requires a highly skilled workforce with robust infrastructure, financial backing and sound programme management coordinated by a strategic plan. Here, the capacity of National M...

    Authors: Tanya L. Russell, Robert Farlow, Myo Min, Effie Espino, Abraham Mnzava and Thomas R. Burkot

    Citation: Malaria Journal 2020 19:422

    Content type: Research

    Published on:

  45. To maintain momentum towards improved malaria control and elimination, a vaccine would be a key addition to the intervention toolkit. Two approaches are recommended: (1) promote the development and short to me...

    Authors: Chetan E. Chitnis, David Schellenberg, Johan Vekemans, Edwin J. Asturias, Philip Bejon, Katharine A. Collins, Brendan S. Crabb, Socrates Herrera, Miriam Laufer, N. Regina Rabinovich, Meta Roestenberg, Adelaide Shearley, Halidou Tinto, Marian Wentworth, Kate O’Brien and Pedro Alonso

    Citation: Malaria Journal 2020 19:421

    Content type: Commentary

    Published on:

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