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  1. In 2005, a nationwide survey estimated that 6.5% of households in Ethiopia owned an insecticide-treated net (ITN), 17% of households had been sprayed with insecticide, and 4% of children under five years of ag...

    Authors: Daddi Jima, Asefaw Getachew, Hana Bilak, Richard W Steketee, Paul M Emerson, Patricia M Graves, Teshome Gebre, Richard Reithinger and Jimee Hwang
    Citation: Malaria Journal 2010 9:58
    Content type: Research Published on:

  2. Previous efforts to eradicate malaria parasites, particularly Plasmodium falciparum, have failed in part due to the emergence of drug resistant parasites and mosquitoes resistant to insecticides. Using an artemis...

    Authors: Jianping Song, Duong Socheat, Bo Tan, Prak Dara, Changsheng Deng, Sreng Sokunthea, Suon Seila, Fengzhen Ou, Huaxiang Jian and Guoqiao Li
    Citation: Malaria Journal 2010 9:57
    Content type: Research Published on:

  3. The use of drug combinations, including non-artemisinin-based and artemisinin-based combination therapy (ACT), is a novel strategy that enhances therapeutic efficacy and delays the emergence of multidrug-resis...

    Authors: Solange Youdom Whegang, Rachida Tahar, Vincent Ngane Foumane, Georges Soula, Henri Gwét, Jean-Christophe Thalabard and Leonardo K Basco
    Citation: Malaria Journal 2010 9:56
    Content type: Research Published on:

  4. Larval mosquito habitats of potential malaria vectors and related species of Anopheles from three provinces (Gyeonggi, Gyeongsangbuk, Chungcheongbuk Provinces) of the Republic of Korea were surveyed in 2007. This...

    Authors: Leopoldo M Rueda, Tracy L Brown, Heung Chul Kim, Sung-Tae Chong, Terry A Klein, Desmond H Foley, Assaf Anyamba, Matthew Smith, Edwin P Pak and Richard C Wilkerson
    Citation: Malaria Journal 2010 9:55
    Content type: Research Published on:

  5. The Tanzanian government recommends women who attend antenatal care (ANC) clinics to accept receiving intermittent preventive treatment against malaria during pregnancy (IPTp) and vouchers for insecticide-trea...

    Authors: Godfrey M Mubyazi, Paul Bloch, Pascal Magnussen, Øystein E Olsen, Jens Byskov, Kristian S Hansen and Ib C Bygbjerg
    Citation: Malaria Journal 2010 9:54
    Content type: Research Published on:

  6. Drug resistance in Plasmodium falciparum is common in many endemic and other settings but there is no clear recommendation on when to change therapy when there is delay in parasite clearance after initiation of t...

    Authors: Akintunde Sowunmi, Elsie O Adewoye, Grace O Gbotsho, Christian T Happi, Abayomi Sijuade, Onikepe A Folarin, Titilope M Okuboyejo and Obaro S Michael
    Citation: Malaria Journal 2010 9:53
    Content type: Research Published on:

  7. Chloroquine was used as first-line treatment for Plasmodium falciparum or Plasmodium vivax in Indonesia before the initial launch of artemisinin combination therapy in 2004. A study to evaluate efficacies of chlo...

    Authors: Inge Sutanto, Dedeh Endawati, Liem Hui Ling, Ferdinand Laihad, Rianto Setiabudy and J Kevin Baird
    Citation: Malaria Journal 2010 9:52
    Content type: Research Published on:

  8. The clinical utility for mefloquine has been eroded due to its association with adverse neurological effects. Better-tolerated alternatives are required. The objective of the present study was the identificati...

    Authors: Erin Milner, William McCalmont, Jayendra Bhonsle, Diana Caridha, Jose Cobar, Sean Gardner, Lucia Gerena, Duane Goodine, Charlotte Lanteri, Victor Melendez, Norma Roncal, Jason Sousa, Peter Wipf and Geoffrey Stuart Dow
    Citation: Malaria Journal 2010 9:51
    Content type: Research Published on:

  9. In many low-income countries, the retail sector plays an important role in the treatment of malaria and is increasingly being considered as a channel for improving medicine availability. Retailers are the last...

    Authors: Edith Patouillard, Kara G Hanson and Catherine A Goodman
    Citation: Malaria Journal 2010 9:50
    Content type: Research Published on:

  10. The activity of promising anti-malarial drugs against Plasmodium gametocytes is hard to evaluate even in vitro. This is because visual examination of stained smears, which is commonly used, is not totally conveni...

    Authors: Séverine Chevalley, Agnès Coste, Alexandrine Lopez, Bernard Pipy and Alexis Valentin
    Citation: Malaria Journal 2010 9:49
    Content type: Methodology Published on:

  11. Controlled clinical trials have shown that a six-dose regimen of artemether-lumefantrine (AL) therapy for uncomplicated Plasmodium falciparum malaria results in cure rates >95% with good tolerability.

    Authors: Abdunoor M Kabanywanyi, Christian Lengeler, Prudensiana Kasim, Said King'eng'ena, Raymond Schlienger, Nathan Mulure and Blaise Genton
    Citation: Malaria Journal 2010 9:48
    Content type: Research Published on:

  12. Malaria remains the most important public health problem in tropical and subtropical areas. Mothers' or caregivers' ability to recognize childhood malaria-related morbidity is crucial as knowledge, attitudes a...

    Authors: Delenasaw Yewhalaw, Wondwossen Kassahun, Kifle Woldemichael, Kora Tushune, Morankar Sudaker, Daniel Kaba, Luc Duchateau, Wim Van Bortel and Niko Speybroeck
    Citation: Malaria Journal 2010 9:47
    Content type: Research Published on:

  13. The merozoite surface protein (MSP)-1 is a target antigen of protective immunity and a malaria vaccine candidate. The nature of this protective immune response warrants further investigation: although specific...

    Authors: Irosoki Eslava, Gilberto Payares, Beatriz M Pernia, Anthony A Holder and Lilian M Spencer
    Citation: Malaria Journal 2010 9:46
    Content type: Research Published on:

  14. Placental malaria (PM) is associated with poor foetal development, but the pathophysiological processes involved are poorly understood. Cyclooxygenase (COX) and lipoxygenase (LOX) which convert fatty acids to ...

    Authors: Demba Sarr, Delphine Aldebert, Laurence Marrama, Emilie Frealle, Alioune Gaye, Hamoud O Brahim, Makhtar Niang, Jean Marie Dangou, Odile Mercereau-Puijalon, Jean Yves Lehesran and Ronan Jambou
    Citation: Malaria Journal 2010 9:45
    Content type: Research Published on:

  15. Scaling up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) with support from the Global Fund and President's Malaria Initiative is providing increased opportunities for malaria con...

    Authors: Raphael N'Guessan, Pelagie Boko, Abibathou Odjo, Joseph Chabi, Martin Akogbeto and Mark Rowland
    Citation: Malaria Journal 2010 9:44
    Content type: Research Published on:

  16. Artemisinin-based combination therapy (ACT) is presently recommended by the World Health Organization as first-line treatment for uncomplicated Plasmodium falciparum malaria in several countries, as a mean of pro...

    Authors: Kanungnit Congpuong, Pongwit Bualombai, Vick Banmairuroi and Kesara Na-Bangchang
    Citation: Malaria Journal 2010 9:43
    Content type: Research Published on:

  17. There have been a number of interventions to date aimed at improving malaria diagnostic accuracy in sub-Saharan Africa. Yet, limited success is often reported for a number of reasons, especially in rural setti...

    Authors: Lisa K Allen, Erin Hetherington, Mange Manyama, Jennifer M Hatfield and Guido van Marle
    Citation: Malaria Journal 2010 9:42
    Content type: Case study Published on:

  18. The effectiveness of malaria chemoprophylaxis is limited by the lack of compliance whose determinants are not well known.

    Authors: Noémie Resseguier, Vanessa Machault, Lénaick Ollivier, Eve Orlandi-Pradines, Gaetan Texier, Bruno Pradines, Jean Gaudart, Alain Buguet, Catherine Tourette-Turgis and Christophe Rogier
    Citation: Malaria Journal 2010 9:41
    Content type: Research Published on:

  19. The island of Timor lies at the south-eastern edge of Indonesia on the boundary of the Oriental and Australian faunal regions. The country of Timor-Leste, which occupies the eastern part of the island, is mala...

    Authors: Robert D Cooper, Michael D Edstein, Stephen P Frances and Nigel W Beebe
    Citation: Malaria Journal 2010 9:40
    Content type: Research Published on:

  20. A moderate association has been found between asymptomatic parasitaemia and undernutrition. However, additional investigation using the gold standard for asymptomatic parasitaemia confirmation, polymerase chai...

    Authors: Benjamin T Crookston, Stephen C Alder, Isaac Boakye, Ray M Merrill, John H Amuasi, Christina A Porucznik, Joseph B Stanford, Ty T Dickerson, Kirk A Dearden, DeVon C Hale, Justice Sylverken, Bryce S Snow, Alex Osei-Akoto and Daniel Ansong
    Citation: Malaria Journal 2010 9:39
    Content type: Research Published on:

  21. Highly purified infected red blood cells (irbc), or highly synchronized parasite cultures, are regularly required in malaria research. Conventional isolation and synchronization rely on density and osmotic fra...

    Authors: Sebastian C Bhakdi, Annette Ottinger, Sangdao Somsri, Panudda Sratongno, Peeranad Pannadaporn, Pattamawan Chimma, Prida Malasit, Kovit Pattanapanyasat and Hartmut PH Neumann
    Citation: Malaria Journal 2010 9:38
    Content type: Methodology Published on:

  22. The Zambia Malaria Indicator Survey (ZMIS) of 2006 was the first nation-wide malaria survey, which combined parasitological data with other malaria indicators such as net use, indoor residual spraying and hous...

    Authors: Nadine Riedel, Penelope Vounatsou, John M Miller, Laura Gosoniu, Elizabeth Chizema-Kawesha, Victor Mukonka and Rick W Steketee
    Citation: Malaria Journal 2010 9:37
    Content type: Research Published on:

  23. Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-...

    Authors: Neils B Quashie, Lisa C Ranford-Cartwright and Harry P de Koning
    Citation: Malaria Journal 2010 9:36
    Content type: Research Published on:

  24. Malaria transmission is now recognized as a key target for intervention. Evaluation of the Plasmodium oocyst burden in the midguts of Anopheles spp. is important for many of assays investigating transmission. How...

    Authors: Michael J Delves and Robert E Sinden
    Citation: Malaria Journal 2010 9:35
    Content type: Methodology Published on:

  25. The efficacy of amodiaquine (AQ), sulphadoxine-pyrimethamine (SP) and the combination of SP+AQ in the treatment of Cameroonian children with clinical malaria was investigated. The prevalence of molecular marke...

    Authors: Wilfred F Mbacham, Marie-Solange B Evehe, Palmer M Netongo, Isabel A Ateh, Patrice N Mimche, Anthony Ajua, Akindeh M Nji, Domkam Irenee, Justin B Echouffo-Tcheugui, Bantar Tawe, Rachel Hallett, Cally Roper, Geoffrey Targett and Brian Greenwood
    Citation: Malaria Journal 2010 9:34
    Content type: Research Published on:

  26. Anopheles cruzii (Diptera: Culicidae) has long been known as a vector of human and simian malaria parasites in southern and south-eastern Brazil. Previous studies have provided evidence that An. cruzii is a speci...

    Authors: Luísa DP Rona, Carlos J Carvalho-Pinto and Alexandre A Peixoto
    Citation: Malaria Journal 2010 9:33
    Content type: Research Published on:

  27. Malaria incidence has been reported to decrease substantially in parts of sub-Saharan Africa, including the Zanzibar Archipelago in East Africa. A cohort study with an intensive follow-up on Pemba Island just ...

    Authors: Thomas Jaenisch, David J Sullivan, Arup Dutta, Saikat Deb, Mahdi Ramsan, Mashavu K Othman, Roger Gaczkowski, James Tielsch and Sunil Sazawal
    Citation: Malaria Journal 2010 9:32
    Content type: Research Published on:

  28. With the increase in use of point-of-care diagnostic tests for malaria and other diseases comes the necessity of storing the diagnostic kits and the drugs required for subsequent management, in remote areas, w...

    Authors: Lon Chanthap, Frédéric Ariey, Duong Socheat, Reiko Tsuyuoka and David Bell
    Citation: Malaria Journal 2010 9:31
    Content type: Research Published on:

  29. Increased investment and commitment to malaria prevention and treatment strategies across Africa has produced impressive reductions in the incidence of this disease. Nevertheless, it is clear that further inte...

    Authors: Bernhards Ogutu, Alfred B Tiono, Michael Makanga, Zulfiqarali Premji, Adama Dodji Gbadoé, David Ubben, Anne Claire Marrast and Oumar Gaye
    Citation: Malaria Journal 2010 9:30
    Content type: Opinion Published on:

  30. Progress towards the development of a malaria vaccine against Plasmodium vivax, the most widely distributed human malaria parasite, will require a better understanding of the immune responses that confer clinical...

    Authors: Carmen Fernandez-Becerra, Sergi Sanz, Marina Brucet, Danielle I Stanisic, Fabiana P Alves, Erney P Camargo, Pedro L Alonso, Ivo Mueller and Hernando A del Portillo
    Citation: Malaria Journal 2010 9:29
    Content type: Research Published on:

  31. Most malaria rapid diagnostic tests (RDTs) use HRP2 detection, including Paracheck-Pf®, but their utility is limited by persistent false positivity after treatment. PLDH-based tests become negative more quickly, ...

    Authors: Sibylle Gerstl, Sophie Dunkley, Ahmed Mukhtar, Martin De Smet, Samuel Baker and Jacob Maikere
    Citation: Malaria Journal 2010 9:28
    Content type: Review Published on:

  33. Plasmodium falciparum is the major species responsible for malaria transmission on the island of Príncipe, in the Republic of São Tomé and Príncipe (STP). Indoor residual spraying (IRS) has been intensively deplo...

    Authors: Pei-Wen Lee, Chia-Tai Liu, Herodes Sacramento Rampao, Virgilio E do Rosario and Men-Fang Shaio
    Citation: Malaria Journal 2010 9:26
    Content type: Research Published on:

  34. With the dramatic drop in the transmission of malaria in Sri Lanka in recent years, the country entered the malaria pre-elimination stage in 2008. Assessing the community prevalence of hidden malaria parasites...

    Authors: Rupika S Rajakaruna, Michael Alifrangis, Priyanie H Amerasinghe and Flemming Konradsen
    Citation: Malaria Journal 2010 9:25
    Content type: Research Published on:

  35. The launch of a new thematic series of Malaria Journal -- "Towards malaria elimination" -- creates the forum that allows carrying scientific evidence on how to achieve malaria elimination in specific endemic sett...

    Authors: Marcel Tanner and Marcel Hommel
    Citation: Malaria Journal 2010 9:24
    Content type: Editorial Published on:

  36. Despite Vietnam's success in reducing malaria mortality and morbidity over the last decade, malaria persists in the forested and mountainous areas of the central and southern provinces, where more than 50% of ...

    Authors: Koen Peeters Grietens, Xa Nguyen Xuan, Wim Van Bortel, Thang Ngo Duc, Joan Muela Ribera, Truong Ba Nhat, Ky Pham Van, Hung Le Xuan, Umberto D'Alessandro and Annette Erhart
    Citation: Malaria Journal 2010 9:23
    Content type: Research Published on:

  37. Entomopathogenic fungi have shown great potential for the control of adult malaria vectors. However, their ability to control aquatic stages of anopheline vectors remains largely unexplored. Therefore, how lar...

    Authors: Tullu Bukhari, Anthonieke Middelman, Constantianus JM Koenraadt, Willem Takken and Bart GJ Knols
    Citation: Malaria Journal 2010 9:22
    Content type: Research Published on:

  38. Combination mosquito nets incorporating two unrelated insecticides or insecticide plus synergist are designed to control insecticide resistant mosquitoes. PermaNet 3.0 is a long-lasting combination net incorpo...

    Authors: Patrick Tungu, Stephen Magesa, Caroline Maxwell, Robert Malima, Dennis Masue, Wema Sudi, Joseph Myamba, Olivier Pigeon and Mark Rowland
    Citation: Malaria Journal 2010 9:21
    Content type: Research Published on:

  39. A recently published comment on a report of Plasmodium knowlesi infections in Vietnam states that this may not accurately represent the situation in the study area because the PCR primers used may cross-hybridize...

    Authors: Peter Van den Eede, Indra Vythilingam, Thang Ngo Duc, Hong Nguyen Van, Le Xuan Hung, Umberto D'Alessandro and Annette Erhart
    Citation: Malaria Journal 2010 9:20
    Content type: Commentary Published on:

  40. Molecular genotyping is performed in anti-malarial trials to determine whether recurrent parasitaemia after therapy represents a recrudescence (treatment failure) or new infection. The use of capillary instead...

    Authors: Vinay Gupta, Grant Dorsey, Alan E Hubbard, Philip J Rosenthal and Bryan Greenhouse
    Citation: Malaria Journal 2010 9:19
    Content type: Research Published on:

  41. Malaria in pregnancy is associated with increased risks of maternal and foetal complications. Currently, intermittent preventive treatment (IPT) of malaria during pregnancy with sulphadoxine-pyrimethamine (SP)...

    Authors: Lucy A Smith, Caroline Jones, Rose O Adjei, Gifty D Antwi, Nana A Afrah, Brian Greenwood, Daniel Chandramohan, Harry Tagbor and Jayne Webster
    Citation: Malaria Journal 2010 9:18
    Content type: Research Published on:

  43. Infection with Plasmodium falciparum during pregnancy contributes substantially to the disease burden in both mothers and offspring. Placental malaria may lead to intrauterine growth restriction or preterm delive...

    Authors: Brigitte Walther, David JC Miles, Sarah Crozier, Pauline Waight, Melba S Palmero, Olubukola Ojuola, Ebrima Touray, Marianne van der Sande, Hilton Whittle, Sarah Rowland-Jones and Katie L Flanagan
    Citation: Malaria Journal 2010 9:16
    Content type: Research Published on:

  44. Information related to malaria vectors is very limited in Bangladesh. In the changing environment and various Anopheles species may be incriminated and play role in the transmission cycle. This study was designed...

    Authors: Mohammad Shafiul Alam, Md Gulam Musawwir Khan, Nurunnabi Chaudhury, Sharmina Deloer, Forida Nazib, A Mannan Bangali and Rashidul Haque
    Citation: Malaria Journal 2010 9:15
    Content type: Research Published on:

  45. Plasmodium falciparum merozoite surface protein-1 (MSP1) has been extensively studied as a blood-stage malaria vaccine candidate, with most work focused on the conserved 19 kDa and semi-conserved 42 kDa C-termina...

    Authors: Sandra P Chang, Alexander KK Kayatani, Zilka I Terrientes, Socrates Herrera, Rose GF Leke and Diane W Taylor
    Citation: Malaria Journal 2010 9:14
    Content type: Research Published on:

  46. Despite clinical descriptions of severe vivax malaria cases having been reported, data regarding immunological and inflammatory patterns are scarce. In this report, the inflammatory and immunological status of...

    Authors: Bruno B Andrade, Antonio Reis-Filho, Sebastião M Souza-Neto, Jorge Clarêncio, Luis MA Camargo, Aldina Barral and Manoel Barral-Netto
    Citation: Malaria Journal 2010 9:13
    Content type: Research Published on:

  47. The G119S mutation responsible for insensitive acetylcholinesterase resistance to organophosphate and carbamate insecticides has recently been reported from natural populations of Anopheles gambiae in West Africa...

    Authors: Luc Djogbénou, Valérie Noel and Philip Agnew
    Citation: Malaria Journal 2010 9:12
    Content type: Research Published on:

  48. Malaria caused by Plasmodium falciparum can result in several different syndromes with severe clinical consequences for the about 200 million individuals infected each year. During pregnancy, women living in ende...

    Authors: Ali Salanti, Mafalda Resende, Sisse B Ditlev, Vera V Pinto, Madeleine Dahlbäck, Gorm Andersen, Tom Manczak, Thor G Theander and Morten A Nielsen
    Citation: Malaria Journal 2010 9:11
    Content type: Research Published on:

  49. Zoonotic malaria caused by Plasmodium knowlesi is an important, but newly recognized, human pathogen. For the first time, post-mortem findings from a fatal case of knowlesi malaria are reported here.

    Authors: Janet Cox-Singh, Jessie Hiu, Sebastian B Lucas, Paul C Divis, Mohammad Zulkarnaen, Patricia Chandran, Kum T Wong, Patricia Adem, Sherif R Zaki, Balbir Singh and Sanjeev Krishna
    Citation: Malaria Journal 2010 9:10
    Content type: Case report Published on:

  50. Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) given during routine vaccinations is efficacious in preventing malaria disease and shows no interaction with the vaccine...

    Authors: Alassane Dicko, Issaka Sagara, Abdoulaye A Djimdé, Sidy O Touré, Mariam Traore, Souleymane Dama, Abdoulbaki I Diallo, Amadou Barry, Mohamed Dicko, Oumar M Coulibaly, Christophe Rogier, Alexandra de Sousa and Ogobara K Doumbo
    Citation: Malaria Journal 2010 9:9
    Content type: Research Published on:
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Malaria Journal

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